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What is Haemopoiesis?
Haemopoiesis, or hematopoiesis, is the process by which new blood cells are formed.
Bone marrow, the tissue inside bones, is one of the most active organs in the body, and is the site where red blood cells, the majority of white blood cells, and platelets are produced.
Site of haemopoiesis :
- Fetus - in the yolk sac, liver or spleen and bone marrow according to the growth of pregnancy.
- Children - the red marrow inside all of the bones makes blood cells.
- Adults - vertebrae, skull, sternum, pelvis.
(all the cells is produced in bone marrow in adult)
Extramedullary Haemopoiesis is production of blood cells outside of bone marrow
*It only happens in fetus stage.
*Can happen to adults if bone marrow is no longer functional or cannot keep up with the production
*Cause spleen and liver to enlarged.
Inside the bone marrow, cells called hematopoietic stem cells are able to produce all the different types of blood cells.
They form either lymphoid stem cells or myeloid stem cells.
- Lymphoid stem cells migrate to the spleen, lymph nodes and thymus and go on to produce lymphocytes, which are white blood cells involved in the immune system's response to infection.
- Myeloid stem cells develop into red blood cells, which carry oxygen, and white blood cells known as granulocytes, megakaryocytes and monocytes. Granulocytes and monocytes help fight off infection, while megakaryocytes break into fragments to form platelets, which are involved in blood clotting.
So easy to understand! Tq btw
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